This state-of-the-art review highlights that patients undergoing two-stage revision arthroplasty for periprosthetic joint infection (PJI) often experience prolonged interstage immobility, leading to functional decline, muscle atrophy, reduced range of motion, and increased risk of medical complications. The authors emphasize the significant psychological and social burden associated with limited mobility, including increased anxiety, depression, caregiver dependence, social isolation, and reduced quality of life. A major conclusion is that standardized mobility assessments are lacking in this population, and that treatment strategies which shorten or eliminate the interstage period may improve clinical outcomes, functional recovery, and overall patient well-being.
Authors: Hari K. Parvataneni, MD; Chancellor F. Gray, MD; Hernan A. Prieto, MD; Larry Yost, Emilie N. Miley, PhD
Partner Institutions: Florida Orthopaedic Institute, University of Florida, The Atticus Group, LLC, Florida State University
